SIBO Treatment With Probiotics – A Promising Study

Probiotic treatment herbal medicine functional medicine byron bay byron shire australia

Antibiotic use is the number one approach to dealing with dysbiosis, SIBO and gut infections of all kinds. As an alternative, herbal antimicrobials can be used. Generally they are much less damaging on the gut microbiome but still they take a toll on the resident population, friendly or less-than-friendly.

Often a probiotic is recommended alongside the antimicrobial approach to lessen the blow to the microflora. It surprised me to learn that certain probiotics, more popular in Europe than here in Australia, actually secrete antimicrobial peptides and bacteriocins.

 

Introducing Bacillus spp.

The genus of bacteria Bacillus is a gram positive aerobic bacteria that is found in asian fermented foods like natto and are also used as a starter culture for soybean ferments in West Africa. Not all strains and species of the genus Bacillus are friendly and some are implicated in food poisoning and food spoilage. Careful selection of certain strains and species is made to ensure human appropriate probiotics (1).

Bacillus clausii has been investigated, with success, for its potential to aid in the treatment of Helicobacter pylori by reducing certain side-effects from the heavy hitting triple-therapy which consists of two antibiotics and an acid suppressing drug (2).

 

Treating the Gut with Bugs Not Drugs

The most exciting paper on Bacillus used a probiotic containing Bacillus clausii to treat SIBO patients. 40 SIBO positive patients, confirmed by an abnormal breath test, were given the Bacillus clausii probiotics three times daily for thirty days.

One month after the probiotic intervention ended each patient retested for SIBO using the same glucose breath test. Incredibly 47% of the patients had cleared the SIBO confirmed by negative, or normal, breath tests.

Unfortunately this research didn’t incorporate the gold standard randomised, blinded control trial but at least it is a good start. Even the possibility of being able to treat small intestinal bacterial overgrowth with probiotics as opposed to antibiotics (pharmaceutical or herbal) is promising.

Perhaps the answer to future and more successful treatments for SIBO, dysbiosis and parasite infections is a combination of both. I’m sure we will see more promising research in the future looking into treating with bugs and not drugs.

 

References and Resources

  1. Diversity and applications of Bacillus bacteriocins.
  2. Bacillus clausii therapy to reduce side-effects of anti-Helicobacter pylori treatment: randomized, double-blind, placebo controlled trial.
  3. Bacillus clausii as a treatment of small intestinal bacterial overgrowth.

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2 comments

  1. The human microbiome, especially in the ‘gut,’ is comprised of diverse populations of bacteria. Further, it’s been found that diversity, not just high doses of a singular type of bacteria are going to help. And finally, the delicacy of the bacterial balance in the microbiome is so touchy, that it only really favors specific types of bacteria– among other factors that determine whether or not the bacteria or colony will stick in the gut. Anything otherwise is merely transient in nature.

    I guess what I’m trying to say is stop being a shill for products that don’t and won’t work. Probiotics of the future (like 5-15 years down the line), maybe, will work but research still has a long way to go with this field.

    1. 100% agree with everything you’ve said about the microbiome and the need for more research. I do think that we can benefit from the research that is out there on SIBO and probiotic use. I’ve seen half a dozen trials showing benefit from lactobacillus spp, bifidobacteria spp, the bacillus bacteria in this article and even yeast microorganisms like saccharomyces cerevisiae var. boulardii. If you come across anything interesting let me know!

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